Product Description of 4-Bromopyridine hydrochloride CAS#19524-06-2
At ambient temperature and normal air pressure, 4-Bromopyridine hydrochloride exists in the form of white crystalline particles. This heterocyclic salt carries moisture-absorbing traits and tends to become deliquescent once exposed to moisture-rich aquatic surroundings.
Within organic synthetic workflows, it can act as a coupling agent and the starting substance for manufacturing various pyridine-based derivatives. Alkaline treatment is generally required before usage so as to liberate free 4-bromopyridine. Thanks to the coordinating capability of its pyridine ring framework, the substance also works as a construction unit when assembling supramolecular-structured chemicals.
4-Bromopyridine hydrochloride Chemical Properties
| Melting point | 270 °C (dec.)(lit.) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water |
| form | Powder |
| color | White to peach |
| Water Solubility | Soluble in DMSO, Methanol and Water. |
| Sensitive | Hygroscopic |
| BRN | 3621847 |
| InChIKey | MPZMVUQGXAOJIK-UHFFFAOYSA-N |
| CAS DataBase Reference | 19524-06-2(CAS DataBase Reference) |
| EPA Substance Registry System | Pyridine, 4-bromo-, hydrochloride (19524-06-2) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38-20/21/22 |
| Safety Statements | 26-36-36/37/39-22 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| F | 46091 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29333999 |
Product Application of 4-Bromopyridine hydrochloride CAS#19524-06-2
4-Bromopyridine hydrochloride serves as a practical heterocyclic building-block in fine-organic synthesis. It is frequently adopted as a coupling reagent to construct diversified pyridine-derived molecules for pharmaceutical-intermediate research.
After alkali neutralization to obtain free-state 4-bromopyridine, the raw-material takes part in cross-coupling reactions for preparing anti-inflammatory and anti-bacterial drug precursors. Benefiting from the coordination capacity of its pyridine ring, it can also be utilized for assembling supramolecular materials.
Apart from medical-chemical research, this hygroscopic compound is applied for laboratory-scale reagent preparation. It needs air-tight preservation, and operators should wear proper gear to prevent skin irritation during operation.
