Products Description of 2-Amino-5-Methyl-3-Thiophenecarbonitrile CAS#138564-58-6
Belonging to heterocyclic organosulfur substances, 2-Amino-5-Methyl-3-Thiophenecarbonitrile carries the molecular formula C6H6N2S. The raw-material sample exhibits pale-yellow to brown crystalline-powder appearance and gains good solubility within methanol solvent. Its measured melting-point range falls between 101-103°C, while its estimated boiling-point value reaches 318.5 ± 42.0°C. Thanks to its unique thiophene-ring framework, this chemical works as an indispensable synthetic building-block, chiefly adopted for manufacturing olanzapine and other related pharmaceutical substances.
2-Amino-5-Methyl-3-Thiophenecarbonitrile Chemical Properties
| Melting point | 101-103°C |
| Boiling point | 318.5±42.0 °C(Predicted) |
| density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 0.16±0.10(Predicted) |
| color | Light yellow to Brown |
| InChIKey | YGXADLPRHBRTPG-UHFFFAOYSA-N |
| CAS DataBase Reference | 138564-58-6(CAS DataBase Reference) |
| Hazard Codes | Xi,Xn |
| Risk Statements | 20/21/22-22 |
| Safety Statements | 22-36/37/39 |
| RIDADR | 3276 |
| HazardClass | IRRITANT |
| HS Code | 29349990 |
Product Application of 2-Amino-5-Methyl-3-Thiophenecarbonitrile CAS#138564-58-6
2-Amino-5-Methyl-3-Thiophenecarbonitrile is a valuable thiophene-based heterocyclic intermediate in the fine-chemical and pharmaceutical sectors. Its reactive amino and cyano groups enable multiple ring-modification reactions for constructing complex bio-active molecular frameworks.
Its most prominent usage lies in the synthetic route of olanzapine, a well-known medicine applied for mental-disorder management. Besides mainstream drug-making, the substance is also utilised for laboratory-level exploration on novel thiophene derivatives. Researchers modify its molecular-chain structure to screen prospective antibacterial and nervous-system-regulating compounds, offering fundamental precursors for new-drug research and related organic-chemistry projects.
